Identification of a naturally-occurring canine model for early detection and intervention research in high grade urothelial carcinoma

Bladder cancer is more prevalent in dogs than people, and Scottish Terriers have a 20 times higher risk of getting this cancer. Using the Scottish Terrier as a model, Purdue investigated the feasibility of early detection and interventional research by studying Scotties. Their goal is to improve outcomes for both humans and dogs with bladder cancer.

Invasive, high grade bladder cancer in people and dogs carries a very guarded prognosis. Treatment often involves radical surgery or radiation therapy, followed by chemotherapy and immunotherapy. The 5-year survival rate is low. Purdue University continues to lead the way in research for this cancer in canines. In this novel study, Purdue incorporates specialists from both Johns Hopkins and the University of Chicago in a One Health approach.

We are excited as this research incorporating the canine model is expected to lead to improved outcomes for humans, as well as pet dogs, facing bladder cancer.

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Information regarding Purdue University’s urinary bladder cancer trial, please click here.